Mutation-Induced Pocket Deactivation: How Ser353/Pro245 Alters KCa2.2 vs KCa3.1 Ligand Selectivity
Matteo Gozzi, Joana Massa, Oliver Koch
This study identifies Ser353/Pro245 as the key structural determinant for ligand selectivity differences between KCa2.2 and KCa3.1 channels using computational methods.
Archiv der Pharmazie · Jul 1, 2026Peer-reviewedPharmacology & Toxicology