Pharmacology & ToxicologybioRxivPreprint
Modulation of the agonist and antagonist activity of peptidic FPR1 ligands through N-terminal modifications: A structural and functional analysis
DOI 10.64898/2026.07.10.737841
Author
Oliver Koch
University of MünsterORCID 0000-0001-9228-217XUnclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2026-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 27 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship3 shared papersPharmacology & Toxicology
Joana MassaORCID
Mutual co-authors in cluster
3 papers
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- Pharmacology & ToxicologyArchiv der PharmaziePeer-reviewed
Mutation-Induced Pocket Deactivation: How Ser353/Pro245 Alters KCa2.2 vs KCa3.1 Ligand Selectivity
Matteo Gozzi, Joana Massa, Oliver Koch
This study identifies Ser353/Pro245 as the key structural determinant for ligand selectivity differences between KCa2.2 and KCa3.1 channels using computational methods.
DOI 10.1002/ardp.70299 - Pharmacology & ToxicologybioRxivPreprint
Discovery of the first small-molecule extracellular inhibitor of KCa3.1
Joana Massa, Jurek Hense, Tanja Gangnus…·Oliver Koch
This paper discovers a small-molecule inhibitor of KCa3.1 channels by combining molecular dynamics simulations and high-throughput screening.
DOI 10.64898/2026.03.08.710400