Matthew J. Fisher

Modeling the genomic architecture of adiposity and anthropometrics across the lifespan

This study models the genomic architecture of adiposity and anthropometrics across the lifespan, identifying shared and distinct genetic factors and their associations with health outcomes.

Enabling reproducible type 1 diabetes polygenic risk scoring for clinical and translational applications

This paper develops a pipeline for translating type 1 diabetes polygenic risk scores into clinical use, showing they can distinguish type 1 from type 2 diabetes and identify high-risk individuals.

Characterizing substructure via mixture modeling in large-scale genetic summary statistics

Summix2 uses mixture modeling to estimate and adjust for substructure in genetic summary data, improving the robustness and equity of research using diverse datasets.