Author

Matthew L. Paff

The University of Texas at Austin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1

Frequent Co-Authors

Bartram L. SmithiD· 2 shared Benjamin R. JackiD· 2 shared Claus O. WilkeiD· 2 shared Daniel R. BoutziD· 2 shared James J. BulliD· 1 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersSystems Biology

Bartram L. SmithORCID

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2 papers

Recent·Most cited

Transcript degradation and codon usage regulate gene expression in a lytic phage

Benjamin R. Jack, Daniel R. Boutz, Matthew L. Paff, Bartram L. Smith, Claus O. Wilke

This study shows that transcript degradation and codon usage regulate gene expression in bacteriophage T7 through a dynamic interplay between transcription, translation, and transcript degradation.

Virus Evolution · Jul 1, 2019Peer-reviewedSystems Biology

Reduced protein expression in a virus attenuated by codon deoptimization

Benjamin R. Jack, Daniel R. Boutz, Matthew L. Paff, Bartram L. Smith, James J. Bull, Claus O. Wilke

The paper investigates how codon deoptimization in bacteriophage T7 reduces protein expression and viral fitness by halving translation of key genes.

G3 Genes Genomes Genetics · Jul 11, 2017Peer-reviewedSystems Biology