Bartram L. Smith

This study shows that transcript degradation and codon usage regulate gene expression in bacteriophage T7 through a dynamic interplay between transcription, translation, and transcript degradation.

The paper investigates how codon deoptimization in bacteriophage T7 reduces protein expression and viral fitness by halving translation of key genes.

This study presents a comprehensive transcriptomics and proteomics dataset of E. coli under 34 growth conditions, revealing differences between exponential and stationary phases and differential gene expression under specific stresses.