Integrating Multiplexed Imaging and Multiscale Modeling Identifies Tumor Phenotype Transformation as a Critical Component of Therapeutic T Cell Efficacy
John W. Hickey, Eran Agmon, Nina B. Horowitz, Matthew Lamore, John B. Sunwoo, Markus W. Covert, Garry P. Nolan
The paper integrates multiplexed imaging and multiscale modeling to show that T cell phenotype influences tumor phenotype conversion, critical for therapeutic efficacy.
bioRxiv · Dec 6, 2023 · PreprintSystems Biology