Antigen avidity drives the durability of the vaccine immune response.
Nicole G. Weidner, Mauricio V. Padilla, Layne Pruitt, Christopher A. Cottrell, Kristyn A. Gonzales, Oleksandr Kalyuzhniy, Michael Kubitz, Nushin B. Alavi, Nicole Phelps, Meredith Weglarz, William R. Schief, Robert K. Abbott
This study shows that antigen avidity affects the durability and diversity of vaccine-induced immune responses by influencing germinal center dynamics and B cell outcomes.
bioRxiv · Apr 18, 2025 · PreprintImmunology