Inferring differentiation trajectories from T cell clonotype distributions
Mariia V. Guryleva, Maximilian Danielsson, Christopher Andrew Tibbitt, Jonathan M. Coquet, Ben Murrell
This paper introduces PhyloTrajectory, a method that uses TCR clonotype frequencies and scRNA-seq to infer T cell differentiation trajectories.
bioRxiv · Jul 2, 2026 · PreprintBioinformatics