Low Dose Methotrexate has Divergent Effects on Cycling and Resting Human Hematopoietic Stem and Progenitor Cells
Maximilien Lora, Henri André Ménard, Anastasia Nijnik, David Langlais, Marie Hudson, Inés Colmegna
This study shows low dose methotrexate (LD-MTX) differentially affects cycling and resting human hematopoietic stem and progenitor cells (HSPC), reducing proliferation while preserving clonogenicity in non-cycling cells.
Clinical and Translational Science · Apr 27, 2025Peer-reviewedImmunology