The Type VI secretion effector TpeX expands the pore-forming virulence arsenal of Pseudomonas aeruginosa
Chantal Soscia, Sébastien Reig, Delphine Lefèbvre, Maximilien Rouzaud, Laura Schmitt, Bérengère Ize, Gaël Brasseur, Sophie Bleves
This study identifies TpeX as a pore-forming T6SS effector in P. aeruginosa that disrupts bacterial membranes, with its activity regulated by an immunity protein.
bioRxiv · Aug 24, 2026 · PreprintMicrobiology