Author

Delphine Lefèbvre

Centre National de la Recherche ScientifiqueORCID 0009-0000-7287-8785Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

Bérengère IzeiD· 2 shared Chantal Soscia· 2 shared Sophie BlevesiD· 2 shared Adeline GouletiD· 1 shared Gaël BrasseuriD· 1 shared L. Schmitt· 1 shared Laura Schmitt· 1 shared Maximilien Rouzaud· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

Bérengère IzeORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintAug 24, 2026

The Type VI secretion effector TpeX expands the pore-forming virulence arsenal of Pseudomonas aeruginosa

Chantal Soscia, Sébastien Reig, Delphine Lefèbvre…·Sophie Bleves

This study identifies TpeX as a pore-forming T6SS effector in P. aeruginosa that disrupts bacterial membranes, with its activity regulated by an immunity protein.

DOI 10.64898/2026.08.24.746647

bacteria (other)proteomics

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MicrobiologyJournal of Biological ChemistryPeer-reviewedMar 31, 2026

Molecular Insights into the bactericidal Toxin Tle1 of Pseudomonas aeruginosa: Interaction with VgrG, its adaptor, and immunity protein

Delphine Lefèbvre, Chantal Soscia, L. Schmitt…·Sophie Bleves

This study characterizes Tle1, a bactericidal toxin from Pseudomonas aeruginosa, and identifies its interactions with VgrG4a, Tla1, and Tli1a, revealing the molecular mechanisms of its delivery and inhibition.

DOI 10.1016/j.jbc.2026.111416

bacteria (other)protein structure

𝕏 PostBluesky