Ion Channel Reaction Networks: Dielectric Screening and the Importance of Off-Pathway Flux
Hannah Weckel-Dahman, Ryan Carlsen, Alexander Daum, Maxwell He, Tyler G. Southam, Jessica M. J. Swanson
This paper uses multiscale responsive kinetic modeling to study ion channel mechanisms, showing that off-pathway flux and dielectric screening significantly influence current profiles and channel behavior.
Journal of Chemical Theory and Computation · Mar 18, 2025Peer-reviewedBiophysics