Ryan Carlsen

The paper links experimentally observed ion flux with microscopic mechanistic properties of ion channels by analyzing how voltage and chemical potential affect transport, identifying the rate-limiting step.

This paper develops a mathematical framework to relate ion channel properties to I-V and I-μ relationships, revealing mechanistic insights into open-channel flux and rectification.

This paper uses multiscale responsive kinetic modeling to study ion channel mechanisms, showing that off-pathway flux and dielectric screening significantly influence current profiles and channel behavior.

This paper introduces a kinetic modeling framework that integrates multiscale simulations and experimental data to quantify biomolecular reaction flux under varying electrochemical conditions.

The paper uses kinetic models to explore how electrical and chemical potentials influence ion transport properties, revealing insights into rectification and saturation mechanisms in ion channels.