Cerebellar mitochondrial dysfunction coincides with structural and behavioral abnormalities in 3q29Del mice
May K Kretzer, Elizabeth Arnulfo Candelario, Ryan Montalvo, Xinyan Leng, Jonathan A. Coello, Zihui Ou, Aaron E. Pozo‐Aranda, Jacob Ellegood, Jennifer Gladys Mulle, Zhen Yan, Ryan H. Purcell, Meike E. van der Heijden
This study shows that 3q29Del mice exhibit reduced cerebellar volume, motor and vocal impairments, and mitochondrial dysfunction, mirroring human 3q29Del phenotypes.
bioRxiv · Sep 30, 2026 · PreprintNeuroscience