Structural basis of RNA polymerase II transcription on the H3-H4 octasome
Cheng-Han Ho, K. Nozawa, Masahiro Nishimura, Mayuko Oi, Tomoya Kujirai, Mitsuo Ogasawara, Haruhiko Ehara, Shun‐ichi Sekine, Yoshimasa Takizawa, Hitoshi Kurumizaka
This study shows that RNA polymerase II transcribes the H3-H4 octasome more efficiently than the nucleosome, with distinct pausing patterns and stepwise tetramer disassembly.
bioRxiv · May 13, 2025 · PreprintMolecular Biology