Haruhiko Ehara

The paper investigates how RNA polymerase II transcribes through an OLDN, finding higher efficiency from the hexasome side and revealing conformational changes during transcription.

The paper investigates how specific acetylation sites on histone H3 affect RNAPII transcription through nucleosomes using cryo-EM structures.

The paper reveals how Set2 deposits H3K36me3 on reassembled nucleosomes during transcription elongation using Cryo-EM structures of the EC-Set2-nucleosome complex.

This study shows that RNA polymerase II transcribes the H3-H4 octasome more efficiently than the nucleosome, with distinct pausing patterns and stepwise tetramer disassembly.

The paper reports cryo-EM structures of the Rat1-Rai1-Rtt103 complex and RNAPII complexes from yeast, revealing the mechanism of mRNA transcription termination by Rat1 exonuclease.

This study identifies ERK2's role in regulating TOP2B phosphorylation to facilitate transcriptional activation of immediate early genes.

This study reveals the unidirectional chloride transport mechanism in NM-R3 using TR-SFX, showing conformational changes and halide binding site insights.