Intestinal epithelial Casd1 influences mucus sialic acid O-acetylation and tissue damage susceptibility toward large-intestinal mucosal insults.
Simin Jafaripour, Mackenzie Melvin, Megan Turluk, Emily Howard, Noah Fancy, Madison Schwagele, Hongyuan Zhang, Jackline D W Irungu, Brian R. Wasik, Daniel Chou, Nitin, Caixia Ma, Qiaochu Liang, Negin Kazemian, Clara A. Letef, , Kirk Bergstrom
This study investigates the role of Casd1 in sialic acid O-acetylation of intestinal mucus and its impact on tissue damage susceptibility in mice.
iScience · Oct 29, 2026Peer-reviewedCell Biology