Evolution guided tolerance engineering of Pseudomonas putida KT2440 for production of the sustainable aviation fuel precursor isoprenol
Hyun Gyu Lim, Aparajitha Srinivasan, Russel Navarro Menchavez, Ian Sofian Yunus, Myung Hyun Noh, Megan White, Yan Chen, Jennifer W. Gin, Bernhard Ørn Palsson, Taek Soon Lee, Christopher J. Petzold, Thomas Eng, Aindrila Mukhopadhyay, Adam M. Feist
This study uses adaptive laboratory evolution and rational engineering to improve Pseudomonas putida's tolerance to isoprenol, enhancing its production of a sustainable aviation fuel precursor.
Metabolic Engineering · May 19, 2025Peer-reviewedMicrobiology