Characterization of tumor interactions with the immune system in an autochthonous mouse model of glioblastoma
Margarita Lui, Olivia Makinson, Meghan L Walsh, Taj J Matthews, John Woulfe, Michele Ardolino, Ian A. J. Lorimer
This paper studies immune responses in a mouse model of glioblastoma, finding that large tumors induce immune responses at border sites but also generate immunosuppressive necroses that limit therapeutic benefit.
bioRxiv · May 15, 2026 · PreprintCancer Biology