Connecting the Microenvironmental Niche to Treatment Response in Ovarian Cancer
Maximilian Strobl, Matthew Wicker, Vikram Adhikarla, W. Andrew Shockey, Eszter Lakatos, Pantea Pooladvand, Ryan Schenk, Linggih Saputro, Chandler Gatenbee, Martijn Koppens, Salvador Cruz García, Robert Wenham, Mehdi Damaghi, Jill A. Gallaher
This study develops a mathematical model to analyze spatial interactions in ovarian cancer microenvironments and shows how niche composition affects treatment response.
bioRxiv · Oct 24, 2018 · PreprintCancer Biology