Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases
Mohamad Karaky, Gabrielle Boucher, Saraï Mola, Sylvain Foisy, Claudine Beauchamp, Marie-Ève Rivard, Melanie Burnette, Hugues Gosselin, Alain Bitton, Guy Charron, Philippe Goyette, John David Rioux
The paper identifies four IBD-associated genes that regulate calprotectin expression in myeloid cells and shows their role in prostaglandin signaling pathways linked to IBD susceptibility.
PLoS Genetics · Sep 26, 2022Peer-reviewedGenetics