Thyroid hormone and ALK5 inhibitor improve maturation of human pluripotent stem cell derived hepatocytes
Sarah Withey, Dave T. Gerrard, Hannah C. Leeson, Rebecca Atkinson-Dell, Sean Philip Harrison, Melissa A. Baxter, Ernst Jurgen Wolvetang, Neil A. Hanley
The paper improves the maturation of human pluripotent stem cell-derived hepatocytes using thyroid hormone and ALK5 inhibitor, enhancing markers of adult liver function.
bioRxiv · Apr 28, 2022 · PreprintDevelopmental Biology