Sarah Withey

The paper shows that activating MIXL1 in hiPSCs improves endoderm differentiation and maturation.

The paper improves the maturation of human pluripotent stem cell-derived hepatocytes using thyroid hormone and ALK5 inhibitor, enhancing markers of adult liver function.

This study investigates epigenetic reprogramming in pig primordial germ cells, identifying similarities with human germline processes and potential for transgenerational epigenetic inheritance.

The paper maps histone modifications across thirteen human tissues during organogenesis to understand gene regulation and link noncoding mutations to developmental disorders.

The paper analyzes pig embryos at single-cell resolution to study lineage segregation, pluripotency, and X-chromosome inactivation during early development, revealing conserved mechanisms with human embryos.