Dave T. Gerrard

The paper identifies TEAD1 as a repressor of tissue-specific transcription factors in human organ development by analyzing combinatorial TF binding in enhancers.

The paper investigates the role of common regulatory and protein-coding TYR variants in albinism, finding a high-frequency promoter variant modulates penetrance of a missense change and a haplotype associated with increased albinism risk.

The paper improves the maturation of human pluripotent stem cell-derived hepatocytes using thyroid hormone and ALK5 inhibitor, enhancing markers of adult liver function.

The paper maps histone modifications across thirteen human tissues during organogenesis to understand gene regulation and link noncoding mutations to developmental disorders.