Point mutations of the mitochondrial chaperone TRAP1 affect its functions and pro-neoplastic activity.
Claudio Laquatra, Alessia Magro, Federica Guarra, Matteo Lambrughi, Lavinia Ferrone, Giulio Fracasso, Melissa Bacchin, Martina La Spina, Elisabetta Moroni, Elena Papaleo, Giorgio Colombo, Andrea Rasola
This study examines how point mutations in TRAP1 affect its structure, function, and pro-neoplastic activity using molecular dynamics simulations and structural analysis.
Cell Death and Disease · Mar 12, 2025Peer-reviewedCancer Biology