Claudio Laquatra

This study shows TRAP1 forms redox-sensitive tetramers via disulfide bonds, which are critical for its antioxidant and pro-neoplastic functions in cancer cells.

This study examines how point mutations in TRAP1 affect its structure, function, and pro-neoplastic activity using molecular dynamics simulations and structural analysis.

This study shows that STAT3 and HIF1α work together to mediate hypoxia responses by physically interacting and enhancing HIF1α transcriptional activity.