Neuronal loss of Galnt2 in Mice Impairs O-glycosylation and Recapitulates Neurological Features of GALNT2-CDG
Andrew C. Edmondson, Melody Yu, Alvin Villarosa, Emily J. Shiplett, John Hintze, Sergey Y. Vakhrushev, Katrine T.-B. G. Schjoldager
This study shows that loss of Galnt2 in mice leads to neurological symptoms similar to GALNT2-CDG and identifies O-glycosylation changes in the brain.
bioRxiv · Sep 30, 2024 · PreprintNeuroscience