Author

Mengdie Yao

Westlake University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 1 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:phylogenetics / evolution· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Huan Liu· 2 shared Jinhong Lu· 2 shared Qing Yang· 2 shared Xing Wu· 2 shared Yanmei DouiD· 2 shared Yiheng Du· 2 shared Yonghe Xia· 2 shared Zhirui Yang· 2 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersBioinformatics

Huan Liu

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2 papers

Recent·Most cited

Detection of Somatic Point Mutations Directly from Spatial Transcriptomics Enables in vivo Spatiotemporal Lineage Tracing

Zhirui Yang, Mengdie Yao, Qing Yang, Yiheng Du, Jinhong Lu, Xing Wu, Jinran Lin, Zhuoyu Qian, Song Hu, Yonghe Xia, Huan Liu, Qiji Zhou, Xiaoyu Ma, Yan Luo, Wenxuan Fan, , Yanmei Dou

SpaceTracer detects somatic SNVs from spatial transcriptomics data to enable lineage tracing in human tissues, revealing tumor progression and immune cell migration.

bioRxiv · Feb 6, 2026 · PreprintBioinformatics

PhyloSOLID: Robust phylogeny reconstruction from single-cell data despite inherent error and sparsity

Qing Yang, Yuheng Liu, Jijian Yang, Xing Wu, Zhirui Yang, Yonghe Xia, Yunchao Zheng, Jinhong Lu, Mengdie Yao, Yiheng Du, Huan Liu, Nan Li, Yanmei Dou

PhyloSOLID improves phylogenetic reconstruction from single-cell data by addressing error and sparsity, achieving better accuracy than existing methods.

bioRxiv · Feb 6, 2026 · PreprintBioinformatics