Author

Wenxuan Fan

Westlake University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Yanmei DouiD· 3 shared Yonghe Xia· 3 shared Chunyi Wang· 2 shared Jinhong Lu· 2 shared Qing Yang· 2 shared Weixiang WangiD· 2 shared Xiaoyu Ma· 2 shared Chong ChuiD· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBioinformatics

Yanmei DouORCID

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Author profile →

3 papers

Recent·Most cited

Unravelling genome-wide mosaic microsatellite mutations at single-cell resolution

Chunyi Wang, Wenxuan Fan, Weixiang Wang, Yonghe Xia, Jinhong Lu, Xiaoyu Ma, Jichuan Yu, Yunchao Zheng, Qing Yang, Meizhen Lin, X F Yu, Xushen Xiong, M Kellis, Qi Xie, Yanmei Dou, Data Group

The paper develops BayesMonSTR to detect mosaic STR mutations at single-cell resolution and finds increased STR indels in aging cells, particularly in prefrontal cortex neurons.

bioRxiv · Apr 5, 2026 · PreprintBioinformatics

Accurate detection of mosaic mutations at short tandem repeats from bulk sequencing data

Weixiang Wang, Wenlong Li, Chunyi Wang, Wenxuan Fan, Yonghe Xia, Xiaoxu Yang, Chong Chu, Yanmei Dou

BulkMonSTR detects mosaic STR mutations in bulk sequencing data with improved precision and F1 scores compared to existing methods.

bioRxiv · Apr 1, 2026 · PreprintBioinformatics

Detection of Somatic Point Mutations Directly from Spatial Transcriptomics Enables in vivo Spatiotemporal Lineage Tracing

Zhirui Yang, Mengdie Yao, Qing Yang, Yiheng Du, Jinhong Lu, Xing Wu, Jinran Lin, Zhuoyu Qian, Song Hu, Yonghe Xia, Huan Liu, Qiji Zhou, Xiaoyu Ma, Yan Luo, Wenxuan Fan, , Yanmei Dou

SpaceTracer detects somatic SNVs from spatial transcriptomics data to enable lineage tracing in human tissues, revealing tumor progression and immune cell migration.

bioRxiv · Feb 6, 2026 · PreprintBioinformatics