Author

Mengke Jiang

Northeastern University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

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Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Hai PaniD· 1 shared Lujun Zou· 1 shared Tingting LiuiD· 1 shared Weitong ReniD· 1 shared Yi CaoiD· 1 shared Yonghua Jiao· 1 shared Yunqiang BianiD· 1 shared Zilong GuoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Hai PanORCID

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1 paper

Recent·Most cited

Dynamic Pathway of Guanidine-III Riboswitch Folding Revealed by Single-Molecule FRET: Mg2+-Assisted Preorganization and Ligand-Induced Kinetic Trapping

Mengke Jiang, Yunqiang Bian, Lujun Zou, Tingting Liu, Zongzhou Ji, Weitong Ren, Zilong Guo, Yi Cao, Yonghua Jiao, Hai Pan

This study uses smFRET and MD simulations to reveal the dynamic conformational changes of the guanidine-III riboswitch, showing how Mg2+ and ligand binding stabilize and trap its folded state.

ACS Chemical Biology · Oct 21, 2025Peer-reviewedBiophysics