Author

Zilong Guo

University of Chinese Academy of SciencesORCID 0000-0002-5652-2583Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:fluorescence / live-cell microscopy· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Hai PaniD· 1 shared Lujun Zou· 1 shared Mengke Jiang· 1 shared Tingting LiuiD· 1 shared Weitong ReniD· 1 shared Yi CaoiD· 1 shared Yonghua Jiao· 1 shared Yunqiang BianiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperBiophysics

Hai PanORCID

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1 paper

Recent·Most cited

Dynamic Pathway of Guanidine-III Riboswitch Folding Revealed by Single-Molecule FRET: Mg2+-Assisted Preorganization and Ligand-Induced Kinetic Trapping

Mengke Jiang, Yunqiang Bian, Lujun Zou, Tingting Liu, Zongzhou Ji, Weitong Ren, Zilong Guo, Yi Cao, Yonghua Jiao, Hai Pan

This study uses smFRET and MD simulations to reveal the dynamic conformational changes of the guanidine-III riboswitch, showing how Mg2+ and ligand binding stabilize and trap its folded state.

ACS Chemical Biology · Oct 21, 2025Peer-reviewedBiophysics