Author

Mette Mathiesen Janiurek

University of Copenhagen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:imaging· 2 Research Focus:spatial domain detection· 2

Frequent Co-Authors

Krzysztof KucharziD· 3 shared Martin LauritzeniD· 3 shared Christina ChristofferseniD· 2 shared Anders Hay‐SchmidtiD· 1 shared Brian DellaValleiD· 1 shared Christoffer Knak GothiD· 1 shared Hans Heugh WandalliD· 1 shared Nikolay P. KutuzoviD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersNeuroscience

Krzysztof KucharzORCID

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3 papers

Recent·Most cited

Two-photon microscopy of brain endothelial glycocalyx uncovers spatial heterogeneity, vesicular transport, and lectin-binding kinetics in the living brain

Oleg Zhukov, Nikolay P. Kutuzov, Teddy Groves, Mette Mathiesen Janiurek, Sally Dabelsteen, Anders Hay‐Schmidt, Hans Heugh Wandall, Christoffer Knak Goth, Brian DellaValle, Martin Lauritzen, Krzysztof Kucharz

This study uses two-photon microscopy to reveal structural and dynamic features of the brain endothelial glycocalyx, including spatial heterogeneity, vesicular transport, and lectin-binding kinetics in vivo.

bioRxiv · Dec 17, 2025 · PreprintNeuroscience

Two-photon microscopy in vivo reveals brain vessel type-specific loss of glycocalyx caused by apoM/S1P signaling impairment.

Krzysztof Kucharz, Mette Mathiesen Janiurek, Christina Christoffersen, Martin Lauritzen

The paper uses two-photon microscopy to show that S1P signaling impairment causes glycocalyx loss in arterioles but not other vessel types in Apom-/- mice.

bioRxiv · Apr 11, 2022 · PreprintNeuroscience

Apolipoprotein M-bound sphingosine-1-phosphate regulates blood-brain barrier paracellular permeability and transcytosis

Mette Mathiesen Janiurek, Rana Soylu-Kucharz, Christina Christoffersen, Krzysztof Kucharz, Martin Lauritzen

This study shows that apoM-bound S1P regulates BBB permeability and transcytosis, with S1PR1 agonists able to restore permeability in apoM-deficient mice.

eLife · Nov 25, 2019Peer-reviewedNeuroscience