Author

Michael Bruderek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Cornelia Rüb· 2 shared Giovanna Cenini· 2 shared Wolfgang Voos· 2 shared Anne Wilkening· 1 shared Marc Sylvester· 1 shared Witold Jaworek· 1 shared

Activity by Year

2016-2016 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

Cornelia Rüb

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2 papers

Recent·Most cited

IMiQC: a novel protein quality control compartment protecting mitochondrial functional integrity

Michael Bruderek, Witold Jaworek, Anne Wilkening, Cornelia Rüb, Giovanna Cenini, Marc Sylvester, Wolfgang Voos

The paper identifies IMiQC as a mitochondrial compartment that sequesters misfolded proteins to maintain mitochondrial function under proteotoxic stress.

bioRxiv · Sep 14, 2016Cell Biology

Amyloid β-peptides interfere with mitochondrial preprotein import competence by a co-aggregation process

Giovanna Cenini, Cornelia Rüb, Michael Bruderek, Wolfgang Voos

This study shows that Aβ peptides inhibit mitochondrial preprotein import by co-aggregating with precursor proteins, contributing to AD pathophysiology.

bioRxiv · Sep 14, 2016Cell Biology