Phosphorylation of the Smooth Muscle Master Splicing Regulator RBPMS Regulates its Splicing Activity
Michael D. Barnhart, Yi An Yang, Erick E Nakagaki-Silva, Thomas H Hammond, Mariavittoria Pizzinga, Clare Gooding, Katherine M. Stott, Christopher W. J. Smith
This study shows that phosphorylation of RBPMS at Thr113 and Thr118 reduces its splicing activity, mediated by ERK2, and may regulate SMC splicing during vascular injury.
Nucleic Acids Research · Nov 11, 2022Peer-reviewedMolecular Biology