DNA binding contributes to dominant-negative effects of a catalytically inactive RecQ4-family helicase
Robert H Simmons, Faith E. McDevitt, Alexandra Hurlock, Michael E. Kumcu, Matthew L. Bochman
The paper investigates how a catalytically inactive RecQ4-family helicase causes dominant-negative effects in DNA repair by showing DNA binding contributes to toxicity.
Nucleic Acids Research · Sep 7, 2026Peer-reviewedMolecular Biology