Charting the Multi-level Molecular Response to Palbociclib in ER-Positive Breast Cancer
Archishma Kavalipati, Amy Aponte, Michael E. Sullivan, Sarah L. Whittington, José C. Martínez, Grant A. Goda, Maria M. Aleman, Michael J. Emanuele, Daniel Dominguez
This study identifies multi-level molecular changes in ER-positive breast cancer cells treated with palbociclib, revealing feedback loops and alternative splicing that suggest new therapeutic strategies.
bioRxiv · Aug 27, 2025 · PreprintMolecular Biology