Characterization of a potential antibiotic target site on the ribosome
Michael Golstein, Yang Wang, Sandra Byju, Udayan Mohanty, Paul C. Whitford
The paper identifies a novel antibiotic target site on the bacterial ribosome by showing how small molecules binding to ribosomal protein L33 can impede translation through steric obstruction.
bioRxiv · May 2, 2025 · PreprintBiophysics