Udayan Mohanty

The paper develops a theoretical model to study how ionic interactions influence subunit rotation in the yeast ribosome, showing that ion concentration changes significantly affect the energy landscape and kinetics of rotation.

The paper identifies a novel antibiotic target site on the bacterial ribosome by showing how small molecules binding to ribosomal protein L33 can impede translation through steric obstruction.

This paper introduces a CRISPR-mediated platform for intracellular directed evolution of RNA aptamers, identifying novel orthogonal aptamer-RBP pairs for multiplexed gene regulation.

The paper introduces SMOG 2, a software package for designing and simulating structure-based biomolecular models using XML templates and PDB structures.