Author

Michael J. Brenan

1Cellbio (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Alan J. SimmonsiD· 2 shared Austin N. Southard-SmithiD· 2 shared Bob CheniD· 2 shared Ken S. LauiD· 2 shared Qi LiuiD· 2 shared Angela JonesiD· 1 shared Cherie’ R. Scurrah· 1 shared Cody N. HeiseriD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersGenomics

Alan J. SimmonsORCID

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2 papers

Recent·Most cited

A contamination focused approach for optimizing thesingle-cell RNA-seq experiment

Deronisha Arceneaux, Zhengyi Chen, Alan J. Simmons, Cody N. Heiser, Austin N. Southard-Smith, Michael J. Brenan, Yilin Yang, Bob Chen, Yanwen Xu, Eun-Young K. Choi, Joshua David Campbell, Qi Liu, Ken S. Lau

The paper develops contamination-focused metrics and software to optimize scRNA-seq experiments by reducing ambient contamination through experimental adjustments.

iScience · Jun 28, 2023Peer-reviewedGenomics

Dual indexed design of in-Drop single-cell RNA-seq libraries improves sequencing quality and throughput

Austin N. Southard-Smith, Alan J. Simmons, Bob Chen, Angela Jones, Marisol A. Ramirez Solano, Paige N. Vega, Cherie’ R. Scurrah, Yue Zhao, Michael J. Brenan, Jiekun Xuan, Martha J. Shrubsole, Ely B. Porter, Xi Chen, Colin J. H. Brenan, Qi Liu, , Ken S. Lau

The paper introduces a dual-indexed library design for scRNA-seq to improve sequencing quality and throughput on high-throughput sequencers.

BMC Genomics · Jul 2, 2020Peer-reviewedMolecular Biology