Paige N. Vega

The paper identifies a pathobiont-epithelial IDO1 pathway that drives region-specific susceptibility to inflammatory bowel disease in the ascending colon.

The paper identifies a novel epithelial cell type, LND, in Crohn's disease that is associated with immune dysregulation and disease activity.

This study maps tumor evolution and microenvironment dynamics in colorectal cancer using spatial multi-omic data, identifying key genes associated with immune exclusion and prognosis.

The paper presents a pipeline for cell segmentation and quantification in complex tissue images using machine learning and deep learning methods.

The paper develops a translation model to identify integrin signaling in anti-TNF-resistant Crohn’s disease and validates it using single-cell RNA sequencing.

The paper introduces a dual-indexed library design for scRNA-seq to improve sequencing quality and throughput on high-throughput sequencers.