Author
Vanderbilt University Medical CenterORCID 0000-0002-1565-4360Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Amy Longtin, Marina M. Watowich, Baptiste Sadoughi…·Amanda J. Lea
The paper optimizes a reduced representation DNA methylation sequencing protocol for cost-effective, population-scale studies across species.
Benjamin Vaisvil, Daniel P. Schmitt, Angela Jones…·Stephen W. Clark
The paper analyzes the DNA sequence and methylome of Jonathan, a 192-year-old giant tortoise, to identify epigenomic features associated with extreme longevity.
Taralynn Mack, Caitlyn Vlasschaert, Kelly von Beck…·Alexander G. Bick
The paper introduces a cost-effective CHIP assay, identifies 101 CHIP cases in a cohort, and finds heterogeneity in clonal expansion rates by driver gene and individual.
Cody N. Heiser, Alan J. Simmons, Frank L. Revetta…·Ken S. Lau
This study maps tumor evolution and microenvironment dynamics in colorectal cancer using spatial multi-omic data, identifying key genes associated with immune exclusion and prognosis.
Austin N. Southard-Smith, Alan J. Simmons, Bob Chen…·Ken S. Lau
The paper introduces a dual-indexed library design for scRNA-seq to improve sequencing quality and throughput on high-throughput sequencers.
Andrew A. Hardigan, Brian S. Roberts, Dianna E. Moore…·R Myers
The paper introduces MAD-DASH, a CRISPR/Cas9-based method to remove adapter dimers and highly expressed smRNAs from small RNA sequencing libraries, improving quantification of low-abundance species.