Behavioral and cortical arousal from sleep, muscimol-induced coma, and anesthesia by direct optogenetic stimulation of cortical neurons
Rong Mao, Matías Cavelli, Graham Findlay, Kort Driessen, Michael J. Peterson, William Marshall, Giulio Tononi, Chiara Cirelli
This study shows that optogenetic stimulation of cortical neurons can awaken mice from sleep, coma, and anesthesia, indicating cortical sufficiency for arousal.
iScience · May 6, 2024Peer-reviewedNeuroscience