Oral LNAD+ Rapidly Elevates Intracellular NAD and Metabolic Flux Without Elevating Circulating NAD: Evidence from a Randomized Controlled Trial
Sergey A. Kornilov, Waylon James Hastings, Lynne Fahey McGrath, Michael Leitz-Langan, Andrew T. Magis, Steve M. Coppess, Wendy Komac
This paper reports that oral LNAD+ rapidly increases intracellular NAD without elevating circulating NAD, showing compartment-specific effects and safety in a clinical trial.
bioRxiv · Apr 27, 2026 · PreprintSystems Biology