Waylon James Hastings

This paper reports that oral LNAD+ rapidly increases intracellular NAD without elevating circulating NAD, showing compartment-specific effects and safety in a clinical trial.

This paper introduces a framework to build saliva-based DNA methylation biomarkers, demonstrating a new epigenetic clock (InflammAge) that quantifies systemic chronic inflammation and outperforms CRP in several health outcomes.

The paper compares epigenetic aging clocks across different tissue types, finding significant differences in age estimates between oral and blood-based tissues.

The paper compares telomere length and DNA quality metrics across five tissues in individuals aged 8 to 70 years, finding age-related shortening in most tissues and tissue-specific variations in DNA quality.

This study evaluates how DNA extraction methods and lab factors affect qPCR-based telomere length measurement precision across multiple labs.

The paper examines how early-life adversity affects gene expression and physiological responses to acute stress in young adults, finding higher cortisol and lower NR3C1 expression in the ELA group.