Importins recognize the winged-helix fold of ETS transcription factors to mediate nuclear import
Michael McConville, Kaylee P. Lankford, Natália Elisa Bernardes, Abby Walterscheid, Catherine Valadez, Ashley B. Niesman, Yuh Min Chook, Glen Liszczak
The paper identifies the ETS domain as a structure-encoded NLS recognized by importins, revealing how importins mediate nuclear import of ETS transcription factors.
Proceedings of the National Academy of Sciences · May 1, 2026Peer-reviewedBiochemistry