Comprehensive modeling of Spinal Muscular Atrophy in Drosophila melanogaster
Ashlyn M. Spring, Amanda C. Raimer, Christine D. Hamilton, Michela J. Schillinger, A. Gregory Matera
This study models spinal muscular atrophy in Drosophila using patient-derived missense mutations, showing similar phenotypes to human SMA across multiple adult neuromuscular metrics.
Frontiers in Molecular Neuroscience · May 16, 2019Peer-reviewedNeuroscience