Synthetic repertoires derived from convalescent COVID-19 patients enable discovery of SARS-CoV-2 neutralizing antibodies and a novel quaternary binding modality
Jule Goike, Ching‐Lin Hsieh, Andrew P. Horton, Elizabeth C. Gardner, Foteini Bartzoka, Nianshuang Wang, Kamyab Javanmardi, Andrew S. Herbert, Shawn A. Abbasi, Rebecca L. Renberg, Michael J. Johanson, José Cardona, Thomas H. Segall-Shapiro, Ling Zhou, Ruth Helmus Nissly, , Jimmy Gollihar
The paper identifies SARS-CoV-2 neutralizing antibodies from convalescent patients and describes a novel quaternary binding mechanism using high-throughput methods.
bioRxiv · Apr 7, 2021 · PreprintSynthetic Biology