Genotype-specific differences in infertile men due to loss-of-function variants in M1AP or ZZS genes
Nadja Rotte, Jessica E. M. Dunleavy, Michelle D. Runkel, Daniela Fietz, Adrian M. E. Pilatz, Johanna Kuß, Ann‐Kristin Dicke, Sofia Boeg Winge, Sara Di Persio, Christian Ruckert, Verena Nordhoff, Hans-Christian Schuppe, Kristian Almstrup, Sabine Kliesch, Nina Neuhaus, , Corinna Friedrich
The paper identifies genotype-specific meiotic impairments in infertile men with loss-of-function variants in M1AP or ZZS genes, showing different recombination failures and reproductive outcomes.
medRxiv · Mar 20, 2024 · PreprintGenetic & Genomic Medicine