Daniela Fietz

Spermatogonial stem cells and their differentiation roadmap throughout marmoset development

This study identifies transcriptional states and regulators of spermatogonial stem cell differentiation in marmoset testes across developmental stages.

Genotype-specific differences in infertile men due to loss-of-function variants in M1AP or ZZS genes

The paper identifies genotype-specific meiotic impairments in infertile men with loss-of-function variants in M1AP or ZZS genes, showing different recombination failures and reproductive outcomes.

TRIM71 deficiency causes germ cell loss during mouse embryogenesis and promotes human male infertility

This study shows TRIM71 is essential for germ cell development in mice and links TRIM71 variants to human male infertility.

Biallelic mutations in M1AP are a frequent cause of meiotic arrest leading to male infertility

The paper identifies biallelic M1AP mutations as a cause of meiotic arrest and male infertility through whole exome sequencing and cohort screening.