Sofia Boeg Winge

The paper introduces a method to estimate gene conversion tract length and rate from PacBio HiFi data, showing low visibility of NCO events in human sperm due to low SNV density.

This study uses long-read sequencing to analyze gene conversion and crossover events in human, chimpanzee, and gorilla testes and sperm, revealing species-specific patterns and GC bias in gene conversion.

The paper shows that X-chromosome loss in Sertoli cells enables maturation and focal spermatogenesis in Klinefelter syndrome.

The paper identifies genotype-specific meiotic impairments in infertile men with loss-of-function variants in M1AP or ZZS genes, showing different recombination failures and reproductive outcomes.